Sequencing Larger Genomes
Über den Vortrag
Der Vortrag „Sequencing Larger Genomes “ von Georgina Cornwall, PhD ist Bestandteil des Kurses „Genomics“.
Quiz zum Vortrag
Which sequencing method is used to cut the DNA of an entire chromosome into small fragments, clone them, and arrange the overlapping sequences?
- Shotgun sequencing
- Clone-by-clone sequencing
- Consensus sequencing
- STS sequencing
- BAC-to-BAC sequencing
Which of the following best describes the clone-by-clone sequencing method?
- Cloning of larger chromosomes and then subcloning them into smaller pieces for sequencing
- Cloning of smaller DNA molecules into a plasmid for sequencing
- Cloning of viral DNA molecules into a human chromosome for sequencing
- Cloning of plasmid DNA molecules into a human chromosome for sequencing
- Cloning of bacterial DNA molecules into a human chromosome for sequencing
Which of the following statements is NOT true regarding the shotgun method of sequencing?
- The shotgun method of sequencing works well with highly repetitive types of DNA molecules.
- The whole-genome shotgun method involves the sequencing of overlapping DNA fragments in parallel and assembling small fragments into larger fragments and then into chromosomes by using a computer program.
- The whole-genome shotgun method is rapid and straightforward versus the clone-by-clone sequencing method.
- Any genome with a lot of repetitive sequences is associated with difficulties during chromosome assembly.
- A genome with few repeated regions can be easily and rapidly sequenced using the whole-genome shotgun method.
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Dozent des Vortrages Sequencing Larger Genomes
Georgina Cornwall, PhD
Dr. Georgina Cornwall is a Biology Instructor and currently works as an Instructional Designer in the private sector, developing interactive online training materials.
She obtained her PhD in Environmental, Population, and Organismic Biology at the University of Colorado, USA, in 2000, and has since taught a broad array of biology courses at various US universities.
She is an active promoter of hybrid/online teaching formats and interactive courses, and has received several awards for her engaging and innovative course design; e.g., she was named Adjunct Faculty of the Year at Colorado Mountain College in Aspen twice.
Within Lecturio, Dr. Cornwall teaches courses on Biology & Genetics.
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