Proofread and Repair Mechanisms
Über den Vortrag
Der Vortrag „Proofread and Repair Mechanisms“ von Georgina Cornwall, PhD ist Bestandteil des Kurses „Year 1 - Block 2: Fundamentals of Medicine I“.
Quiz zum Vortrag
What is the primary mechanism of DNA proofreading?
- The 3'-5' exonuclease activity of DNA polymerase
- Photolyase activity
- Excision repair
- Resynthesis by DNA polymerase
- Removal and splicing by telomerase
Which of the following statements are CORRECT regarding mutagens? Select all that apply.
- Mutagens cause errors in DNA.
- Ultraviolet (UV) light causes DNA damage as thymine residues form a dimer.
- Ionization radiation, UV light, reactive oxygen species, polycyclic aromatic hydrocarbons, and transposons are known to cause DNA mutations.
- Mutagens help the enzyme photolyase chop off damaged nucleotide sequences in dsDNA.
- During DNA replication, the mutagen gets associated with DNA polymerase and helps recognize wrongly incorporated nitrogenous bases.
Which of the following is TRUE of photolyase?
- It is a visible light–dependent DNA-repair enzyme specific for UV light–damaged DNA repair.
- It depends on the presence of mutagen molecules to repair damaged DNA.
- It works in association with transposons to repair damaged DNA.
- It creates thymine dimers in the DNA helix to stop the transposition of transposons in a gene.
- It gets activated in the presence of UV light and chops off the transposon DNA from the damaged gene.
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Dozent des Vortrages Proofread and Repair Mechanisms
Georgina Cornwall, PhD
Dr. Georgina Cornwall is a Biology Instructor and currently works as an Instructional Designer in the private sector, developing interactive online training materials.
She obtained her PhD in Environmental, Population, and Organismic Biology at the University of Colorado, USA, in 2000, and has since taught a broad array of biology courses at various US universities.
She is an active promoter of hybrid/online teaching formats and interactive courses, and has received several awards for her engaging and innovative course design; e.g., she was named Adjunct Faculty of the Year at Colorado Mountain College in Aspen twice.
Within Lecturio, Dr. Cornwall teaches courses on Biology & Genetics.
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Very helpful on understanding the basics of the repair mechanisms.
