CRISPR-Cas9 System
Über den Vortrag
Der Vortrag „CRISPR-Cas9 System “ von Georgina Cornwall, PhD ist Bestandteil des Kurses „Biotechnology“.
Quiz zum Vortrag
Clustered regularly interspaced short palindromic repeats (CRISPR) are composed of which of the following?
- A family of DNA sequences containing pieces of DNA from invading viruses that attack the host bacterium
- A family of mRNA sequences containing pieces of mRNA from invading viruses that attack the host bacterium
- A family of signal protein sequences containing pieces of antigens from invading viruses that attack the host bacterium
- A family of signal lipoprotein sequences containing pieces of immunogenic proteins from invading viruses that attack the host bacterium
- A family of signal glycoprotein sequences containing pieces of immunogenic proteins from invading viruses that attack the host bacterium
Which of the following statements is NOT true regarding the CRISPR/Cas9 system?
- The CRISPR/Cas9 system helps in the amplification of viral DNA in host cells by providing adaptive immunity to the incoming virus.
- Viral snippets in the CRISPR of a bacterium play a crucial role in the bacterial defense system against bacteriophages.
- The pre-designed sequence of the guide RNA (gRNA) directs Cas9 nuclease to the right region of the invading DNA molecule such that Cas9 can cleave the foreign DNA.
- Cas9 nuclease cleaves double-stranded DNA at specific sites and activates DSB repair machinery in bacterial cells.
- The CRISPR/Cas9 system can be used as a targeted genome-editing tool in molecular biology.
Which of the following is true regarding the CRISPR/Cas9 system? Select all that apply.
- It is a very specific restriction endonuclease system derived from the bacterial "immune system."
- It is target-specific; thus, we can insert genes specifically as required.
- It shows potential for the future of DNA-based therapies.
- It was designed from scratch to eradicate type-2 diabetes.
- It is a eukaryotic endonuclease that can cut a gene as required.
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Dozent des Vortrages CRISPR-Cas9 System
Georgina Cornwall, PhD
Dr. Georgina Cornwall is a Biology Instructor and currently works as an Instructional Designer in the private sector, developing interactive online training materials.
She obtained her PhD in Environmental, Population, and Organismic Biology at the University of Colorado, USA, in 2000, and has since taught a broad array of biology courses at various US universities.
She is an active promoter of hybrid/online teaching formats and interactive courses, and has received several awards for her engaging and innovative course design; e.g., she was named Adjunct Faculty of the Year at Colorado Mountain College in Aspen twice.
Within Lecturio, Dr. Cornwall teaches courses on Biology & Genetics.
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