G-protein Coupled Receptors – Second Messenger Systems
Über den Vortrag
Der Vortrag „G-protein Coupled Receptors – Second Messenger Systems“ von Georgina Cornwall, PhD ist Bestandteil des Kurses „Cell Signaling (Texas A&M FOM II 2020 Exam Unit 1)“.
Quiz zum Vortrag
Which of the following signaling cascades are in the correct sequence?
- G protein alpha-subunit → adenylyl cyclase → cAMP → PKA → response protein
- G protein alpha-subunit → cAMP → adenylyl cyclase → PKA → response protein
- G protein alpha-subunit → adenylyl cyclase → PKA → cAMP → response protein
- G protein alpha-subunit → PKA→ cAMP → adenylyl cyclase → response protein
- G protein gamma-subunit → adenylyl cyclase → cAMP → PKA → response protein
Which of the following is responsible for the production of cAMP in a G protein–coupled receptor system?
- Adenylyl cyclase
- Guanylyl cyclase
- Phosphokinase
- Protein phosphatase
- Protein diphosphatase
Which of the following is NOT correct regarding phosphatidylinositol-4,5-bisphosphate (PIP-2) and signal transduction?
- Diacylglycerol (DAG) and inositol-1,4,5-triphosphate (IP3) are signal-carrying molecules that bind to the cell membrane receptor during muscle contraction.
- PIP-2 is a membrane phospholipid embedded in the inner leaflet of the cell membrane.
- DAG and IP3 act as second messengers in downstream signaling pathways.
- Phospholipase C acts as an effector protein and hydrolyzes PIP-2 to propagate the muscle cell contraction signaling cascade.
- IP3 and DAG stimulate downstream signaling pathways to facilitate hormone release in endocrine cells.
Which of the following is CORRECT regarding the effect of epinephrine?
- Epinephrine stimulates G protein–coupled receptors in the heart to increase contractions.
- Epinephrine stimulates G protein–coupled receptors in the heart to decrease contractions.
- Epinephrine stimulates G protein–coupled receptors in the small intestines to increase contractions.
- Epinephrine stimulates G protein–coupled receptors in the small intestine, which activates adenylyl cyclase.
- Epinephrine stimulates G protein–coupled receptors in the heart, which inactivates adenylyl cyclase.
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Dozent des Vortrages G-protein Coupled Receptors – Second Messenger Systems
Georgina Cornwall, PhD
Dr. Georgina Cornwall is a Biology Instructor and currently works as an Instructional Designer in the private sector, developing interactive online training materials.
She obtained her PhD in Environmental, Population, and Organismic Biology at the University of Colorado, USA, in 2000, and has since taught a broad array of biology courses at various US universities.
She is an active promoter of hybrid/online teaching formats and interactive courses, and has received several awards for her engaging and innovative course design; e.g., she was named Adjunct Faculty of the Year at Colorado Mountain College in Aspen twice.
Within Lecturio, Dr. Cornwall teaches courses on Biology & Genetics.
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It was a great lesson thanks for everyting short and briefly everyting.
