Pyrimidine de novo Metabolism: ATCase Reaction von Kevin Ahern, PhD

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Über den Vortrag

Der Vortrag „Pyrimidine de novo Metabolism: ATCase Reaction“ von Kevin Ahern, PhD ist Bestandteil des Kurses „Purine and Pyrimidine Metabolism“.


Quiz zum Vortrag

  1. ATCase
  2. PRPP synthetase
  3. PRPP amidotransferase
  4. IMP dehydrogenase
  5. Adenylosuccinate synthetase
  1. ATP and aspartate
  2. CTP and aspartate
  3. GTP and aspartate
  4. UTP and aspartate
  5. TTP and aspartate
  1. The higher concentrations of CTP inhibit the ATCase enzyme and therefore stop the further synthesis of pyrimidine nucleotides.
  2. The higher concentrations of CTP inhibit the ATCase enzyme via a feedback mechanism and hence stop the further synthesis of purine nucleotides.
  3. The higher concentrations of CTP activate the ATCase enzyme, and hence synthesis of pyrimidine nucleotides is enhanced.
  4. The higher CTP concentrations activate the ATCase enzyme, and hence synthesis of purine nucleotides is enhanced.
  5. The higher CTP concentrations activate the ATCase enzyme, and hence synthesis of aspartate is enhanced.
  1. ATCase requires one aspartate to produce carbamoyl aspartate.
  2. ATC requires one asparagine to produce carbamoyl asparagine.
  3. It is activated by CTP and ATP.
  4. It is inhibited by abundant aspartate.
  5. It is inhibited by ATP.

Dozent des Vortrages Pyrimidine de novo Metabolism: ATCase Reaction

 Kevin Ahern, PhD

Kevin Ahern, PhD

Dr. Kevin Ahern is a Professor in the Department of Biochemistry and Biophysics at Oregon State University (OSU), USA.
He obtained his PhD in Biochemistry from Oregon State University. Currently, he teaches courses for health sciences students at OSU.
He is co-author of three Open Educational electronic textbooks on Biochemistry and a Guide to Getting Into Medical School.
Due to his achievements, he earned OSU’s highest teaching recognition, the Elizabeth P. Ritchie Distinguished Professor Award in 2017.
Within Lecturio, Dr. Ahern teaches courses on Biochemistry and on "How to Get into Medical School”.


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von Orel G. am 24. Juni 2017 für Pyrimidine de novo Metabolism: ATCase Reaction

It was very clear and explained well- the subject itself is usually hard to explain