Week 10 (LMU OMS 1 Fall)

Thank you so much, Dr Thad. You're very clever in coming up with the 'gnomes' example, which is perfect for quickly understanding Acid-base. Thanks again.

I've reviewed the Video, and while it provides a comprehensive overview, there are a few points that need clarification. "Fatty acid synthesis doesn't occur in the mitochondrion; it occurs in the cytoplasm, sequestered from fatty acid oxidation, simplifying the regulation of the two pathways." Clarification: Fatty acid synthesis indeed occurs in the cytoplasm, separate from fatty acid oxidation that takes place in mitochondria. This separation allows for streamlined regulation, ensuring the balance between synthesis and breakdown. "Fatty acid synthesis is chemically similar to the reverse of oxidation, involving joining, reduction, loss of water, and a final reduction, making it essentially the reverse of oxidation." Clarification: Fatty acid synthesis does indeed involve joining of acetyl and malonyl units, reduction steps, and removal of water, making it similar but not exactly the reverse of oxidation. The subtle differences in the chemical steps are crucial for the controlled synthesis of fatty acids. "The enzyme acetyl-CoA carboxylase is regulated through phosphorylation by AMP-activated protein kinase and allosteric binding of citrate, ensuring the balance between synthesis and cellular energy levels." Clarification: Acetyl-CoA carboxylase, a key enzyme in fatty acid synthesis, is indeed regulated through phosphorylation and allosteric binding of citrate. This regulation allows cells to respond to energy demands, modulating fatty acid production accordingly. "Fatty acid synthesis involves a series of steps catalyzed by the multifunctional enzyme fatty acid synthase, where individual activities within the enzyme complex work together, ensuring efficient fatty acid production." Clarification: Fatty acid synthase, a multi functional enzyme complex, plays a central role in fatty acid synthesis. Its individual activities work in harmony within the complex, allowing for the sequential addition of carbon units and the creation of fatty acids up to 16 carbons in length.

Thank you! I appreciate how you explain this material. Thank you

knee is a very important joint and this lesson is too short to cover the ligaments.

the accent that the prof. has used is not 100% understandable.

There's some good information in here, but it definitely cannot be taught by itself and will need supplemental textbooks to fill in some of the details.

very nice and concise . Good explanation with beautiful diagrams and interactive learning supplemented with a methodical approach

I really like this lecture very much and I have a learnt a great deal from this.

This video is a good review of Knee examination and maneuvers. I especially liked the meniscal tear examinations.

Beautifully described. Clear and concise presentation. Your all lectures are brilliant

I still don't understand. I have played the video so many times. Maybe its just a very hard concept.

The explanation was quite detailed without leaving the basics. Good illustrations as well.

Great video, however images where too small to follow along and actually understand what he is saying, if these images where larger the class would have been absolutely clear and understandable. Thank you!

it is completely useless. no bursae even mentioned! there is no description of any of the things mentioned. Very disappointing, the joint in general are not well described

A very complete summary to refresh knowledge of the hip. Thanks you!

I would recommend this lecture to someone who has a rough idea of thoracic anatomy as well. This lecture was easy to follow and it made me understand the subject much better.

nowhere near enough detail, too brief to explain the knee joint

This is completely inadequate for the questions posed. The first question gives "you observed red gnomes outside the box on the left for both pH and HCO3" and asks for the condition. Verbatim from the lecture ‘’Respiratory alkalosis’’. Why? Cos there are two gnomes on one side." Yet the answer is metabolic acidosis.

Great explanation, details, logarithms and discussion. Great lecturer, thanks Dr Raj

Well explained and i clearly understand how digestion and absorption be done.

idk what the below review is talking about, this is clearly an introduction-style lecture and it's been done well. does well to get cogs whirring

Anatomy is explained best with annotated images and pointers on the various parts as the lecturer speaks. Not through tabulation of facts.

detailed and explained really well, so that I understood everything. Thank you!

Clean and clear. Simple explanations. He knows the subject for sure.

Very eloquent :) my favorite on this website! would definitely recommend.

Good brief overview of the knee joint but I wish the lecturer would have gone more in-depth about the menisci, and the rotational and translational movements of the knee.

Yea, these lessons site wide need more quiz questions. Only thing holding this site back from being outstanding.

Dr. Wilson, you are my hero, you made this concept of acid base balance so easy for the first time in my life. Thank you so much!!

Dr. James' explanation was very clear. The pictures in the lecture could have been a bit bigger but overall it was delivered very well.

He explains it so well, but I wish there was subtitles

Well explained dr,now i understand better, i liked this class very much

I never would've thought such a complex respiratory concept would be simplified by a bunch of colored garden gnomes. Thanks Dr. Wilson!

multiply things go unexplained... for example, he did not even explain what is the pelvic floor, or what is the pelvic diaphragm, but he quoted it several times.... bad class

I finally understood why keto diet is so effective :) Thank you Dr. Kevin!

it's amazing the example with the gnoms thank you !! easy to learn

The Good: Lecture: 5/5 Amazing Lecture! I learned a lot! The Not so good: Quiz:2/5 Only 1 question....and was not as specific as I would like it to have been. Perhaps consider having at least 50% of the terms discussed included in the Quiz.

On the slide about respiratory compensation for metabolic acidosis, the compensation slope with decrease Pco2 level has a PCO2 value of 60 which should be 20. Becauase in respiratory Compensation for MA PCO2 slightly decreases That is just a typo, but can been confusing The lecture itself is very good

Easy to learn using the box. I always struggled with this, even on my board exam. This box and explanation made it much easier for me as a visual learner.

blue ,red gnomes ,suoer ,really good lecture,clarified,simplified,nice

Dr. Wilson does an excellent job in breaking down concepts of acid-base balance in the body and making it plain. He also provides some additional tricks/tools that you may not get in your regular lectures, but will definitely help on an exam. These lectures are top notch, just excellent!