Steroids and Bile Acids: Mevalonate Pathway II
Über den Vortrag
Der Vortrag „Steroids and Bile Acids: Mevalonate Pathway II“ von Kevin Ahern, PhD ist Bestandteil des Kurses „Lipid Metabolism“.
Quiz zum Vortrag
Which of the following is a cyclic intermediate produced during cholesterol synthesis?
- Lanosterol
- Squalene
- Farnesyl pyrophosphate
- Geranyl pyrophosphate
- Dimethylallyl pyrophosphate
Which of the following statements is FALSE regarding cholesterol synthesis in the body?
- Isopentenyl pyrophosphate (IPP) and dimethylallyl pyrophosphate (DMAPP) are produced from HMG-CoA by the action of the enzyme HMG-CoA reductase in the presence of lanosterol.
- The conversion of HMG-CoA to mevalonate is mediated by an enzyme called HMG-CoA reductase.
- Cholesterol regulates the production of HMG-CoA enzyme through feedback inhibition.
- HMG-CoA reductase enzyme plays a very important role in the regulation of cholesterol synthesis in the body.
- Statin drugs act as competitive inhibitors of HMG-CoA reductase, so it is useful as a cholesterol-lowering drug.
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Dozent des Vortrages Steroids and Bile Acids: Mevalonate Pathway II
Kevin Ahern, PhD
Dr. Kevin Ahern is a Professor in the Department of Biochemistry and Biophysics at Oregon State University (OSU), USA.
He obtained his PhD in Biochemistry from Oregon State University. Currently, he teaches courses for health sciences students at OSU.
He is co-author of three Open Educational electronic textbooks on Biochemistry and a Guide to Getting Into Medical School.
Due to his achievements, he earned OSU’s highest teaching recognition, the Elizabeth P. Ritchie Distinguished Professor Award in 2017.
Within Lecturio, Dr. Ahern teaches courses on Biochemistry and on "How to Get into Medical School”.
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