Regulation of Iron Transport
Über den Vortrag
Der Vortrag „Regulation of Iron Transport“ von Kevin Ahern, PhD ist Bestandteil des Kurses „Amino Acid Metabolism“.
Quiz zum Vortrag
Which of the following is true regarding the iron response element (IRE)?
- It is bound by the IRE-BP when iron concentration is low.
- It is a protein.
- It binds to iron when the iron concentration is high.
- It occurs near the 3' end of the ferritin mRNA.
- It allows the ribosome to perform translation when bound to the IRE-BP.
Which is true regarding the binding of the IRE-BP to the transferrin receptor mRNA?
- It occurs at the 3’ end.
- It protects the 5’ end from nuclease degradation.
- It reduces the synthesis of the receptor.
- It binds to the transferrin mRNA when iron concentrations are high.
- It allows nucleases to degrade the transferrin mRNA.
What happens to ferritin regulation at the low levels of iron inside the cell?
- The IRE-BP binds to the IRE of the ferritin mRNA and blocks the synthesis of ferritin protein.
- The IRE-BP binds to the iron and halts the synthesis of ferritin protein.
- The IRE-BP binds to the iron and facilitates the synthesis of the ferritin protein.
- The IRE-BP binds to the iron and facilitates the binding of iron with the ferritin mRNA.
- The IRE-BP binds to the IRE of the ferritin mRNA and allows for the synthesis of the ferritin protein.
How do the high concentrations of iron regulate the transferrin receptor protein synthesis?
- At high concentrations of iron, the binding of IRE-BP to iron makes transferrin receptor mRNA susceptible to nuclease attack and prevent transferrin receptor protein synthesis
- At high concentrations of iron, the binding of IRE-BP to transferrin receptor mRNA facilitates transferrin receptor protein synthesis
- At high concentrations of iron, the binding of iron to IRE of transferrin receptor mRNA facilitates the synthesis of transferrin receptor protein
- At high concentrations of iron, the binding of IRE-BP to iron and IRE of mRNA facilitates the synthesis of transferrin receptor protein
- At high concentrations of iron, the binding of IRE-BP to iron facilitates the synthesis of transferrin receptor protein
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Dozent des Vortrages Regulation of Iron Transport
Kevin Ahern, PhD
Dr. Kevin Ahern is a Professor in the Department of Biochemistry and Biophysics at Oregon State University (OSU), USA.
He obtained his PhD in Biochemistry from Oregon State University. Currently, he teaches courses for health sciences students at OSU.
He is co-author of three Open Educational electronic textbooks on Biochemistry and a Guide to Getting Into Medical School.
Due to his achievements, he earned OSU’s highest teaching recognition, the Elizabeth P. Ritchie Distinguished Professor Award in 2017.
Within Lecturio, Dr. Ahern teaches courses on Biochemistry and on "How to Get into Medical School”.
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best explanation of the iron transport on the web that I have come across. Good clear diagrams.
this guy so good only amazing so much only omg nice nice
