Purine de novo Metabolism Regulation
Über den Vortrag
Der Vortrag „Purine de novo Metabolism Regulation“ von Kevin Ahern, PhD ist Bestandteil des Kurses „Year 1 - Block 2: Fundamentals of Medicine I“.
Quiz zum Vortrag
Which of the following is true regarding the regulation of purine metabolism? Select all that apply.
- Both of the enzymes acting on IMP are feedback inhibited.
- PRPP amidotransferase is fully inhibited by either AMP or GMP.
- Low phosphate and AMP will inhibit the first enzyme of the pathway.
- ATP inhibits Adenylosuccinate synthetase.
- IMP dehydrogenase is inhibited by GMP.
Which of the following enzyme does NOT participate in the regulation of purine synthesis in the cells?
- Nucleoside diphosphate kinase
- PRPP synthetase
- PRPP amidotransferase
- IMP dehydrogenase
- Adenylosuccinate synthetase
Which of the following is NOT matched correctly?
- Nucleoside diphosphate kinase — inhibited by an excess of ribose-5-phosphate.
- PRPP synthetase — inhibited by high levels of phosphate and ADP.
- PRPP amidotransferase — partly inhibited by AMP or GMP, but fully inhibited by both AMP and GMP.
- IMP dehydrogenase — inhibited by GMP to stop GTP synthesis.
- Adenylosuccinate synthetase — inhibited by AMP to stop ATP synthesis.
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Dozent des Vortrages Purine de novo Metabolism Regulation
Kevin Ahern, PhD
Dr. Kevin Ahern is a Professor in the Department of Biochemistry and Biophysics at Oregon State University (OSU), USA.
He obtained his PhD in Biochemistry from Oregon State University. Currently, he teaches courses for health sciences students at OSU.
He is co-author of three Open Educational electronic textbooks on Biochemistry and a Guide to Getting Into Medical School.
Due to his achievements, he earned OSU’s highest teaching recognition, the Elizabeth P. Ritchie Distinguished Professor Award in 2017.
Within Lecturio, Dr. Ahern teaches courses on Biochemistry and on "How to Get into Medical School”.
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beautifuly explained. thankyou!! Every point in every step was explained nicely.
I loved how I understood the bigger picture in the end of the lecture
