Cooperativity von Kevin Ahern, PhD

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Über den Vortrag

Der Vortrag „Cooperativity“ von Kevin Ahern, PhD ist Bestandteil des Kurses „Amino Acid Metabolism“.


Quiz zum Vortrag

  1. The binding of the first oxygen is the least favorable oxygen binding.
  2. The binding of the last oxygen is the least favorable oxygen binding.
  3. The binding of oxygen turns hemoglobin into the T-state.
  4. In the R-state, hemoglobin can carry three oxygen molecules.
  5. Once the first globin changes to the R-state, all other globins change to the R-state.
  1. With higher affinity than hemoglobin
  2. To the same extent as hemoglobin
  3. With lower affinity than hemoglobin
  4. Irreversibly
  5. Through a process call cooperativity
  1. Myoglobin changes from a relaxed to a tight state at high oxygen concentration levels, favoring oxygen binding.
  2. Cooperativity is displayed by systems having dependently acting identical or near-identical subunits.
  3. Cooperativity of hemoglobin toward oxygen binding in the lungs shows conformational changes from the T state to the R state.
  4. The binding of oxygen on the hemoglobin molecule enhances the affinity of adjacent binding sites for oxygen.
  5. The binding of a ligand to one of the binding sites increases or decreases the affinity of the other binding sites to the ligand.
  1. Cooperativity — binding of oxygen to myoglobin
  2. Oxygen affinity curve for hemoglobin — Sigmoidal
  3. Binding of oxygen to myoglobin — Low concentrations of oxygen
  4. Oxygen affinity curve for myoglobin — Hyperbolic
  5. Oxygen and hemoglobin — Cooperativity

Dozent des Vortrages Cooperativity

 Kevin Ahern, PhD

Kevin Ahern, PhD

Dr. Kevin Ahern is a Professor in the Department of Biochemistry and Biophysics at Oregon State University (OSU), USA.
He obtained his PhD in Biochemistry from Oregon State University. Currently, he teaches courses for health sciences students at OSU.
He is co-author of three Open Educational electronic textbooks on Biochemistry and a Guide to Getting Into Medical School.
Due to his achievements, he earned OSU’s highest teaching recognition, the Elizabeth P. Ritchie Distinguished Professor Award in 2017.
Within Lecturio, Dr. Ahern teaches courses on Biochemistry and on "How to Get into Medical School”.


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