Leucine (LEU), Valine (VAL), Isoleucine (ILE) and Histidine (HIS) Metabolism
Über den Vortrag
Der Vortrag „Leucine (LEU), Valine (VAL), Isoleucine (ILE) and Histidine (HIS) Metabolism“ von Kevin Ahern, PhD ist Bestandteil des Kurses „Amino Acid Metabolism I (Texas A&M FOM II 2020 Exam Unit 1)“. Der Vortrag ist dabei in folgende Kapitel unterteilt:
- Leucine (LEU)/Valine (VAL)/Isoleucine (ILE) Metabolism
- Histidine (HIS) Metabolism
Quiz zum Vortrag
Which of the following is true of branched chain amino acid synthesis?
- It is regulated by threonine deaminase.
- It begins with α-ketobutyrate.
- It favors isoleucine when valine is low.
- Valine and isoleucine pathways involve adding a two-carbon piece to pyruvate.
- They start with decarboxylation and the addition of a three-carbon piece.
Which of the following apply to branched chain amino acid catabolism?
- Leucine metabolism starts with decarboxylation.
- Breakdown of branched-chain amino acids involves transamination.
- It produces NAD+.
- It produces NADH.
- When defective, it results in maple syrup urine disease.
Which of the following is true regarding histidine metabolism?
- It overlaps with nucleotide metabolism.
- It arises from tryptophan metabolism.
- It involves 15 steps.
- Isoleucine inhibits this pathway.
- It is a very simple pathway.
The branched-chain ketoaciduria (maple syrup urine disease) is caused due to the deficiency of which enzyme?
- Branched-chain alpha-keto acid dehydrogenase complex (BCKDC).
- Tyrosine transaminase.
- 4-fumarylacetoacetase.
- Homogentisate oxidase.
- Threonine deaminase.
Histidine amino acid synthesis is controlled by a feedback mechanism involving the interaction of which of the following?
- ATP-phosphoribosyltransferase and histidine.
- Threonine deaminase and threonine.
- Threonine deaminase and histidine.
- ATP-phosphoribosyltransferase and threonine.
- Tyrosine transaminase and histidine.
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Dozent des Vortrages Leucine (LEU), Valine (VAL), Isoleucine (ILE) and Histidine (HIS) Metabolism
Kevin Ahern, PhD
Dr. Kevin Ahern is a Professor in the Department of Biochemistry and Biophysics at Oregon State University (OSU), USA.
He obtained his PhD in Biochemistry from Oregon State University. Currently, he teaches courses for health sciences students at OSU.
He is co-author of three Open Educational electronic textbooks on Biochemistry and a Guide to Getting Into Medical School.
Due to his achievements, he earned OSU’s highest teaching recognition, the Elizabeth P. Ritchie Distinguished Professor Award in 2017.
Within Lecturio, Dr. Ahern teaches courses on Biochemistry and on "How to Get into Medical School”.
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