00:01
Now, before we move on
to the actual anatomic structures
in greater detail,
we're going to talk about
the big picture of circulation.
00:08
That's going to help us
understand the anatomy
to come in the following
sections a lot better.
00:13
Of course,
in order to know that
we actually have to talk
about how circulation differs
before and after birth.
00:20
So we're going to start
with fetal circulation.
00:23
Because in fetal circulation,
oxygenated blood is actually
coming from the placenta,
to the body through
the umbilical vein.
00:33
And I'll stop right there because
you might be wondering,
"Why is the vein carrying
oxygenated blood?
I thought arteries
carry oxygenated blood.
00:41
Veins carry deoxygenated blood.
00:43
And for most systemic arteries
and veins, that is the case,
that's just not
how they're defined.
00:49
Arteries are defined by whether
they're going away from the heart.
00:52
And veins are defined by whether
they're coming toward the heart.
00:55
So the umbilical vein
or for that matter,
the pulmonary veins,
are carrying oxygenated
blood towards the heart.
01:04
So their veins that actually
do carry oxygenated blood.
01:08
So in this sense, it's an oxygenated
blood coming from the placenta,
through the umbilical vein.
01:14
And we really want to
get that oxygenated blood
out to the key body
parts as soon as possible
before using it up
on too many tissues.
01:22
And that's why there's a little
bypass in the area of the liver
called the ductus venosus.
01:29
It's going to shortcut
its way across the liver,
so that it can join the IVC
right before it gets
to the right atrium.
01:38
We haven't wasted too much of
that good oxygenated blood yet.
01:42
And there's a little
curvature to this area
where the IVC joins
the right atrium,
it's going to help direct the flow
of that blood across the heart
directly through this opening
called the foramen ovale,
into the left atrium.
01:59
And this way,
we don't waste any of that blood
going to the lungs,
because at this point,
there's no air being breathed.
It's amniotic fluid.
02:06
The lungs don't really require
a whole lot.
02:10
So we're bypassing the
right ventricle in the lungs
in skipping over
to the left atrium.
02:15
That way, it can go down
into the left ventricle,
and then out into the aorta,
where it can supply those structures
going up into the head and neck,
namely the brain.
02:27
And that's important
to keep in mind.
02:29
Now, we still have blood coming
from the SVC into the right atrium.
02:35
And that's going to be your
traditional deoxygenated
venous blood.
02:39
And some of it's
going to mix with that
good oxygenated blood
coming from the IVC.
02:44
On its way to the right ventricle,
doing the usual flow,
you would expect
where from there,
it's going to go out to the lungs
via the pulmonary trunk.
02:56
But again, at this point,
in utero, there's just fluid,
there's no air being breathed.
03:02
So there's not a large
requirement of blood in the lungs.
03:05
So a lot of that blood is going to
face another bypass or shortcut
called the ductus arteriosus,
and goes straight into the aorta.
03:17
And the cool thing about the
location of the ductus arteriosus
is it's joining after those
branches to the head and neck,
namely the brain have already
pulled off of the aorta.
03:29
And that's good, because that's
the best most oxygenated blood.
03:33
And after the ductus, it's sort
of this mixed oxygenation blood
that's going to supply
the rest of the body
via the other
branches of the aorta.
03:42
And then eventually,
there going to be some
branches down in the pelvis,
called the umbilical arteries
that go back towards the placenta
to start the cycle over again.
03:52
Now, it might be
good news for the brain.
03:54
But if you're thinking - wait,
there's all this mixed oxygenation
supplying the rest of the body,
that doesn't sound very good.
03:59
We want that real good red
colored oxygenated blood.
04:03
The good news is,
the fetus compensates by carrying
the stickier form of hemoglobin
called fetal hemoglobin,
and it's stickier for oxygen.
04:12
And that helps
balance this all out.
04:15
Now, what's going to
happen after birth?
Well, the key thing from
our point of view here
is that there's no more placenta.
04:22
Now, the lungs are going
to replace the placenta
as the source of oxygenated blood.
04:29
And so there are a lot
of consequences to that.
04:31
There is no longer
an umbilical cord.
04:33
So it falls off and we're left with
the stump called the umbilicus,
which is just our fancy
anatomy word for belly button.
04:41
And since there's no blood flowing
through the umbilical vein anymore,
it's lumen just obliterates
and it turns into a ligament
called the round ligament,
or ligamentum teres.
04:52
Teres is just a word
that means round.
04:54
Similarly, the ductus venosus
is going to obliterate
to form the ligamentum venosum.
05:01
The umbilical arteries,
also not needed anymore
are going to obliterate and
form medial umbilical ligaments,
and then up where we had
the ductus arteriosus
it will also close off
and form a ligament
called the ligamentum arteriosum.
05:18
And then that opening
that we took advantage of
to go from right to left
is going to close off.
05:23
So that foramen ovale is going to
seal and become a shallow depression
called the fossa ovalis.
05:30
And we're going to see
a lot of these structures
in some future sections.