00:01
IV fluids, the first classification that we'll
be dealing with will be called crystalloids.
00:09
And the reason that I paused here for crystal
is because I want you to think of these electrolytes
are being crystal and the reason I say that
is all go ahead and introduce the second category
that we'll discuss next and those would be
colloids. And often times as soon as you get
crystalloids and colloids confused, and there
is really no need for that. Here the crystalloids,
the crystals would be the electrolytes and
we primarily are dealing with sodium and
chloride as you can imagine. Now, these do
not readily cross the plasma membrane and
this is something that we have already discussed
in reference to sodium chloride. For example,
once again organization, you have ECF and
ICF. The membrane that separates the ECF and
ICF would then be your plasma or cell membrane
and you know that electrolytes such as sodium
and company do not cross it. Well potassium
will, but that obviously is not brought into
the discussion here whereas the membrane that
separates the ECF, amongst ECF meaning to say
the plasma compartment and also the interstitium
is then separated by a capillary membrane
and then here, of course, your sodium and chloride
would readily cross. Hope that is clear. That
is an organisation pattern that we have established
now throughout the lecture series. Now when
dealing with crystalloids, the .... have getting this
fluid into the plasma or into
the interstitium, overall what have you done?
You have introduced the fluids into the ECF.
01:52
Now with that said, obviously the compartments
that you want to replenish if need be when
a patient has undergone hypovolemic changes
or hypovolemic type of conditions, would be
in fact the plasma compartment. But understand
because of its cost effectiveness that saline
which is a crystalloid including sodium chloride
would be the easiest access point. As you
said now, there is going to be a little bit
of math involved here and it is important
that you at least understand this much. I
am going to give you the most complicated
situation that you might then encounter here
in your medical education. Obviously, when
you go further into specialization there's going
to be a lot more detail required of you, but
let us just keep things at this point at the level
where there is just enough where you can be
successful as you walk into any ward and take
any board. The crystalloid is distributed
equally through the ECF. In the ECF, now the
values that you want to use here technically
would be 1/4 and we have talked about
this plenty. One-fourth would be the plasma
and then 3/4 of this would then be the interstitium.
But overall we are only remaining where? Good. In
the ECF. Examples, normal saline and lactate
ringer or ringers lactate. Some of these crystalloid
is all we're doing here. We haven't gone into
albumin because that is a different category,
right. So all we are doing here is looking
at crystalloids thus we have normal saline
and ringers lactate. So if you have a question,
why isn't fresh frozen plasma here? That is because
well we haven't gotten into colloids, which is
our next discussion.