Succinylcholine: Drug Interactions (Nursing)

00:00 Now, which drugs don't play well with succs? Well, you're going to watch for a more intense effect of succinylcholine if the patient is on a cholinesterase inhibitor. Now, before I break that down, I want you to think through, just pause and think what is cholinesterase based on its name an inhibitor. So, see if you can figure out what this does. Okay, I hope you took advantage of pausing the video and stopping to think because you'll be amazed at yourself at how much you already know. We see it's a-s-e. We know that's an enzyme. We know that enzymes break down things, and then we know that before that is choline, so this is an enzyme that breaks down choline, but this is a cholinesterase inhibitor so that means it's going to block the action of cholinesterase, this enzyme that breaks down choline, so I'm going to have extra. Right? I'm going to have a more intense effect. That's why it potentiates the effects of succinylcholine. So, if someone is taking succinylcholine but they're already on a cholinesterase inhibitor for some other problem, this means that succs is going to be supercharged and powerful. There are also some antibiotics. I've listed them for you, but they can also mess with the intensity of succinylcholine. So, keep that in mind. This is why a history is over important with every patient especially this is an elective procedure. That's why multiple people ask the same questions multiple times. They know they're going to give this drug. These are the things that they're going to look at when they're assessing that patient.