Pancreatic Secretions – Lower Gastrointestinal Secretion

00:01 Hello! Today, we’re going to talk about the lower GI secretions.

00:06 Here, we are going to have a few different learning goals.

00:09 The first is the constituents of mechanisms of pancreatic secretions and how these glands are controlled and regulated.

00:16 Our second goal will be to also know the constituents of the biliary secretions, how bile is stored, and how it is released and regulated.

00:27 Finally, we will understand how cystic fibrosis transmembrane regulators, which are abbreviated CFTR, how they are applied in the GI system and how this works in the formation of the pathophysiology of cystic fibrosis, which is important in terms of one our pathophysiological mechanisms.

00:52 So let’s start off with pancreatic secretions.

00:54 The pancreatic secretions will occur or dump into the small intestine.

01:00 The pancreas is a very large organ and it’s the pancreatic duct that primarily will lower or release its substances into the small intestine.

01:12 The pancreas is made up of two different endocrine kind of glands.

01:16 The pancreatic islets are going to be the alpha and beta cells that are involved with insulin and glucagon secretion.

01:24 And those are not what we’re going to talk about today.

01:27 Today, we’re going to talk about the exocrine portions of the pancreas.

01:30 This will secrete digesting enzymes, water, and bicarbonate.

01:37 So why do we need to secrete these substances? Well, because we need to undergo digestion of carbohydrates, fats and proteins.

01:46 And we will talk through the enzymes that are responsible for each of those particular digestive processes.