Frameshift Mutations
About the Lecture
The lecture Frameshift Mutations by Georgina Cornwall, PhD is from the course DNA Repair & Genetic Mutations.
Included Quiz Questions
Which of the following best describes a frameshift mutation?
- An insertion or deletion of a base pair that alters how each codon is read after that insertion or deletion
- A mutation of a base pair that does not affect a codon
- A mutation that only affects one codon in the DNA sequence
- A repeat of the same three nucleotides in a gene
- A part of the chromosome that gets moved from one region of the chromosome to another
Which of the following is NOT correct about codon reiteration disorders?
- Huntington disease is an example of codon reiteration disorder with two trinucleotide repeats.
- Trinucleotide repeat expansions of genes lead to triplet repeat expansion disorders.
- The expanded CAG repeats lead to the development of Huntington disease.
- Expanding triplet repeats usually expand over the lifetime, which might be associated with disease progression.
- Triplet repeat expansion mutations can occur in both coding and noncoding regions of DNA.
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Author of lecture Frameshift Mutations
Georgina Cornwall, PhD
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