Day 6: Biochemistry – Watch Videos

I've reviewed the Video, and while it provides a comprehensive overview, there are a few points that need clarification. "Fatty acid synthesis doesn't occur in the mitochondrion; it occurs in the cytoplasm, sequestered from fatty acid oxidation, simplifying the regulation of the two pathways." Clarification: Fatty acid synthesis indeed occurs in the cytoplasm, separate from fatty acid oxidation that takes place in mitochondria. This separation allows for streamlined regulation, ensuring the balance between synthesis and breakdown. "Fatty acid synthesis is chemically similar to the reverse of oxidation, involving joining, reduction, loss of water, and a final reduction, making it essentially the reverse of oxidation." Clarification: Fatty acid synthesis does indeed involve joining of acetyl and malonyl units, reduction steps, and removal of water, making it similar but not exactly the reverse of oxidation. The subtle differences in the chemical steps are crucial for the controlled synthesis of fatty acids. "The enzyme acetyl-CoA carboxylase is regulated through phosphorylation by AMP-activated protein kinase and allosteric binding of citrate, ensuring the balance between synthesis and cellular energy levels." Clarification: Acetyl-CoA carboxylase, a key enzyme in fatty acid synthesis, is indeed regulated through phosphorylation and allosteric binding of citrate. This regulation allows cells to respond to energy demands, modulating fatty acid production accordingly. "Fatty acid synthesis involves a series of steps catalyzed by the multifunctional enzyme fatty acid synthase, where individual activities within the enzyme complex work together, ensuring efficient fatty acid production." Clarification: Fatty acid synthase, a multi functional enzyme complex, plays a central role in fatty acid synthesis. Its individual activities work in harmony within the complex, allowing for the sequential addition of carbon units and the creation of fatty acids up to 16 carbons in length.

very precise, for a person with basic knowledge it is very helpful although I think it could be a bit difficult to understand for someone who does not know anything about these issues.

Dr. Ahem explained a complex concept in a very interesting and simple way. Straight to the point and informative. Thank you

All of the videos on this topic are very good, thank you!! It made me finally understand it. I wish we would have more details on the pathologies related to the Purine and Pyrimidine pathways.

Short and simple. Right through to the significant things. Thanks to the professor.

Wonderful, simple and easy-to-understand video. Finally got it

This video has several problems. It does not seem to be a continuation of the previous ones, it has unclear information, the reparation itself is not explained, and the name dropping doesn't help either.

Love this lecture. Dr. Ahern explains much better than my professor.

I FULLY recommend!! Definitely has help out in my courses.

Comprehensive, latest information presented in an easy to understand formats. Thanks!

I liked the way the R and T states where explained. It all became very clear

It was hard to understand It could be better another way to explain the topic

this is amazing thank you , i gained a lot of info about viruses that i have not know before

First of all, I like the depth of this lecture and Professor Ahern is clearly very knowledgeable and concise on the the topic being discussed. And I also like due to the fact that this video is clearly a high-yield resource which is very helpful for my upcoming medical exam. However, I believe that this could have been better had the previous cycles preceding the formation of OMP explained as well in order for us the students to be able to get the essence of the information better. That's all I have got to say

Excellent Lecture from lecturio; I highly recommended for students from medical school. It is an excellent learning platform.

I love lecturio, it's the best app in the world. Lecturio has everything you want and can help you to be the best in your class and also be the doctor you want. Lecturio is an opportunity that can give you the change of your student life.

His explanations are very good. Biochemistry made easy!! He is very good in teaching.

beautifuly explained. thankyou!! Every point in every step was explained nicely.

Amazing way of teaching, compact and efficient. Really good job, keep doing it Mr. Ahern.

Has high yield infos which are not in other lecturer's lectures

My professors at university failed to explain lipid metabolism in an understandable manner. Prof Ahern does a great job in explaining complex topics and I am really grateful for that. Thank you

this presentation was good and the way sir explained the concepts was nice

VERY clear explanation of how this works, I love Ahern's lectures.

It is an xcellent explication! I understend it at all. Thank you

The DNA Repair lecture was not very clear at all.

Very high-yield. Thank you for underlining this moment, crucial in treating hypercholesterolemia.

Actually I saw the YouTube add . And I watched the lecture . The information is given in short and precise manner. Understood everything.

I loved how I understood the bigger picture in the end of the lecture

Very eloquent :) my favorite on this website! would definitely recommend.

A good introduction. Very schematic and overall easy to learn basics.

Nice succinct intro with basic overview -- key points are highlighted

Yea, these lessons site wide need more quiz questions. Only thing holding this site back from being outstanding.

Highly recommended lecturer for Biochemistry! I like his method, he is attractive teacher.

Thanks for focusing on the "big picture!" The lecturer at my school bogged us down with the details, so it was hard to take in what the most important steps were

Brief, understandable, high yield information explained with illustrative slides by Dr. Ahern

This guy deserves a medal. I wish I had a lecturer like this when I was in undergrad (or even now in medical school).

Not bad, but need to identify the polymerases better, as in the replication of DNA and RNA...

Wonderful! An awesome lecturer, he just has a unique way of passing the message. Great work Sir

Great lecturer very knowledgeable of subject matter at an admirable pace. Good job

Great lecturer very knowledgeable of subject matter at an admirable pace. I needed this in med sch. Good job

Great lecturer very knowledgeable of subject matter at an admirable pace. Good job

This guy is on top of his game at a ridiculous speed... I can't complain only if all others know their stuff like him there will be less confusion

Care for details and passion/curiosity for knowledge are seen in this lecture. I gained a lot from it.

Very profesional, why is it said that bacterial chromosome has a single origin of replication and eukaryotic multiple origins

Thank you so much Sir for brief description of all topics.

I finally understood why keto diet is so effective :) Thank you Dr. Kevin!

This lecture was very educational, and well organised, moving from the basics to the complicated topics, explaining every topic step by step.

Excellent lectures. The professor speaks very clearly. He makes it easy to understand.

The Good: Lecture: 5/5 Amazing Lecture! I learned a lot! The Not so good: Quiz:2/5 Only 1 question....and was not as specific as I would like it to have been. Perhaps consider having at least 50% of the terms discussed included in the Quiz.

Kevin must be the best teacher ever. He explains with a certainty only a person with many years of lecturing can. Simple, easy and fast, making complicated matters seem easy to learn. Compared to the slides i have in med. school, the content is the same. But this guy also gives the explaination in the same amount of time! His body language is also nice to watch as they are firm and open, kind of directing your thoughts, like a maestro. You just have to remember and do some repetition of EVERY detail he mentiones, it will for sure be on the exam. I also use his lectures to simplify my understandings from pdf files from school and heavy textbooks. I will recommend everyone to use this!! Also i love the quiz afterwards. 1rst year university medicine

Fantastic lecture, just the amount of information I needed to cover and retain the topic.

few things are missing like discoiling of histone protien and a sentence is not repeates

Brief and comprehensive lectures. Really makes mechanisms and actors really to understand.

Thank you so much Dr Kevin, this lecture series are the best that I have seen so far and explain very well, simple and practical a very complicated topic.

A great, insightful lecturer. A Prof. at the top of his game. Miss his long hair though (checkout his youtube site)!

Easy to understand with the structure of the molecule. Very clear and straight forward.

It was very clear and explained well- the subject itself is usually hard to explain

Very helpful Keep it up .. easy to understand . Lecture in a simple way