00:01
So, now let's turn to the
gallbladder and the biliary tree,
how bile moves
throughout this system.
00:08
So the gallbladder really
is just a small sack
that's located on the inferior
visceral surface of the liver.
00:16
And bile is made by the liver.
00:17
It's an important substance
that helps to emulsify
or break down fats.
00:22
So it needs to pass into
the gastrointestinal tract.
00:24
And it does this by passing
through the major duodenal papilla.
00:28
As we saw previously, in the middle
of the second part of the duodenum.
00:34
What we end up having is
throughout the liver
as we have these intra and
extra hepatic bile ducts.
00:39
And these are really
a network of channels
that allow bile to be filtered down
from the liver towards this region.
00:47
So let's have a look at
this in a bit more detail.
00:50
Let's start by looking
at the gallbladder.
00:52
It has a fundus, which is really
the part that you see sneaking out
from the underside of the liver
against that inferior border.
01:00
We have the main substance of
the body, of the gallbladder
before it narrows and tapers
down towards the neck.
01:06
The channel that connects the
gallbladder to this billary tree
this system is known
as the cystic duct.
01:12
The cystic duct is going to
unite with a common hepatic duct.
01:17
And the common
hepatic duct is formed
from both right and left
hepatic ducts,
which are really drain in both the
left and right side of the liver
of the bile is produced.
01:29
So bile produced by the liver is
fed into this common hepatic duct
via the left and
right hepatic duct.
01:36
It's then met by the cystic duct
to form what we know
as the bile duct.
01:42
The bile duct then runs towards
the main pancreatic duct,
which we can see running along
the inner surface of the pancreas.
01:50
And the main pancreatic duct
is taking pancreatic juice
from the pancreas
that also passes into the duodenum.
01:58
Where the bile duct and the
main pancreatic duct unites,
we have the
hepatopancreatic ampulla.
02:05
This is a large dilation,
where both the bile duct
and the main pancreatic duct
unite the hepatopancreatic ampulla.
02:14
Within the
hepatopancreatic ampulla,
there's then a small opening
the major duodenal papilla,
where this fluid conjoin
the duodeneum.
02:23
So bile is produced in the liver
and runs through the bile duct
all the way to the Ampulla of Vater
or the hepatopancreatic ampulla.
02:32
The Sphincter of Oddi is
a strange name sphincter.
02:35
We can call it the
hepatopancreatic sphincter,
but some textbooks may call it
the sphincter of Oddi is closed.
02:42
If that sphincter is constricted,
then bile will start
going back up this channel
and build up within
the gallbladder.
02:50
So if the sphincter is closed and
bile can't enter into the duodenum.
02:55
It then backs up and is
stored within the gallbladder.
02:59
The liver produces bile.
The gallbladder stores it.
03:04
And whilst it's being
stored in the gallbladder,
it can actually concentrate it
and make it a much richer fluid.
03:10
The problem with that is that
actually overly concentrating bile
can lead to the
creation of gallstones.
03:16
And as it says here,
these are present in roughly 10%
of the population.
03:21
They can actually as they
pass through the gallbladder
actually block some
of this pathway,
and they can become
impacted in the region.
03:28
Known as Hartmann pouch
we can see here.
03:32
Small stones can actually
pass through the bile duct,
into the duodenum, and leave us
naturally without ever knowing.
03:39
But large stones can
actually become impacted
around the sphincter
of the ampulla.
03:44
And therefore, no bile will
then be getting into the system,
and it won't actually be allowed
to escape through the body.
03:51
Because bile is there
naturally in the circulation
because it's then being absorbed
by the circulatory system.
03:57
As that blood goes to
the surface of the body,
and it starts leaving
those blood vessels
due to lower blood pressure,
and it seeps out,
you have the yellow coloration
of the skin, which is jaundice.
04:08
So, if you see that
maybe there's a problem
with your gallbladder
and gall stones.