X-linked Inheritance
Über den Vortrag
Der Vortrag „X-linked Inheritance“ von Georgina Cornwall, PhD ist Bestandteil des Kurses „Single-Gene Disorders“.
Quiz zum Vortrag
What is the probability of hemophilia A in a male offspring if the mother is a carrier?
- 50%
- No probability of an affected male offspring
- 25%
- 75%
- 100%
What is the probability of hemophilia A in a female offspring if the mother is a carrier and the father is normal?
- No probability of an affected female offspring
- 25%
- 50%
- 75%
- 100%
Why might a carrier female display mosaicism in an X-linked recessive disorder?
- Each cell has the ability to form a Barr body with the normal chromosome or with the mutant chromosome.
- They have three X-chromosomes and two will compensate for the mutant allele.
- They have a translocation of the mutant type allele to the wild type chromosome so both alleles can be expressed.
- Two Barr bodies are formed so neither X-chromosome is expressed.
- Transcription factors favor binding the Barr body causing a variable yield of proteins.
Which of the following terms best describes sex-linked genes in a normal human male?
- Hemizygosity
- Homozygosity
- Heterozygosity
- Ambiguity
- Haploidy
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Dozent des Vortrages X-linked Inheritance
Georgina Cornwall, PhD
Dr. Georgina Cornwall is a Biology Instructor and currently works as an Instructional Designer in the private sector, developing interactive online training materials.
She obtained her PhD in Environmental, Population, and Organismic Biology at the University of Colorado, USA, in 2000, and has since taught a broad array of biology courses at various US universities.
She is an active promoter of hybrid/online teaching formats and interactive courses, and has received several awards for her engaging and innovative course design; e.g., she was named Adjunct Faculty of the Year at Colorado Mountain College in Aspen twice.
Within Lecturio, Dr. Cornwall teaches courses on Biology & Genetics.
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Very in-depth discussion of X-linked inheritance. A very good resource for studying for exams on human genetics.
