Nephritic syndrome is not a specific pathologic diagnosis but rather an observed clinical syndrome that encompasses the constellation of decreased urine output, hematuria, and resultant edema and hypertension. The causative pathology common to each of the causes of nephritic syndrome is glomerular inflammation, which leads to the acute appearance of red blood cells and red blood cell casts in the urine, as well as white blood cells in the urine and variable proteinuria. Although the primary pathology may be renal, nephritic syndrome is often a manifestation of underlying systemic disorders. For this reason, a diagnosis of nephritic syndrome should prompt a detailed review of symptoms and clinical history for secondary causes.
Infection-related glomerulonephritis, IgA nephropathy, lupus nephritis, membranoproliferative glomerulonephritis, and antineutrophil cytoplasmic antibody-associated vasculitis are the most common diseases in nephritic syndrome that clinicians might encounter in practice, and a solid comprehension of these can lead to earlier detection.
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I couldnt understand the pathology for so long. I am so glad for the clear diagrams and interesting talk.
Professor Amy Sussman's course on nephrology in general, and this section in particular, is well-organized, clearly explained and made such a difficult topic easy to understand and a joy to study.
Amazing, simple but detailed, great lecturer, she made the all difficult Nephrology an enjoyable informative breeze. Thanks Dr. Sussman.
I was struggling between Pauci and Anti Basement(Goodpasture) now my concept is very clear.