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Hello everyone, welcome to Cardiovascular Disease. Our specific topic here is hypertension.
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Dr. Raj, let's start. We'll begin with hypertension. 130/80 mmHg, that is the cut off point to
define hypertension, 130 systole, 80 diastole. Stage 1 hypertension extends until 139/89.
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Stage 2 hypertension is blood pressure higher than or equal to 140/90. Now, what do you
need to confirm hypertension? At least 2 separate measurements over at least 2 separate
office visits. Once you have confirmed hypertension, you should understand at what point
you need to administer therapy immediately instead of proceeding with further laboratory
testing, lifestyle changes, or non-pharmacologic therapy. Blood pressure higher than 180
systolic over 120 diastolic accompanied by evidence of organ damage should be treated
immediately. Anything that we do moving forward, you need to make sure that you confirm
your diagnosis always. Those are type of questions that you shall get from every single
source, let it be rotations, let it be your residency, let it be any licensing exam. Now, once
you go beyond 130/80, what do you need to do? You want to make sure that you understand
at what point you need to administer therapy immediately. What does that mean? Well, as we
proceed to a hypertension, we will take a look at the differences between primary and
secondary. We will be spending a little bit more time on secondary because the exact etiology
and pathogenesis become quite obvious to us in the journey towards secondary hypertension
becomes very relevant. Primary hypertension, for the most part, we'll be thinking about telling
your patient "Hey, we wanted you to lose some weight." Now you're not going to come out
and say that, that wouldn't be very nice. So what do you say? Hmmm. "What are you eating?
Would you wanna cut down on salt perhaps?" Salt, what is that? Sodium. Hmmm. So you'll
start thinking about sodium and its effects on your blood pressure. Whenever sodium is
present in your plasma in your blood, guess what it's going to do, it's going to retain some of
that fluid, huh. So all I'm doing here is giving you a better idea, more detail-oriented
pathophys so that you understand how to deal with something like primary hypertension. As
your blood pressure continues to rise, you want to start thinking about "Wow, do I need to
administer immediate therapy."? A diastole of 120, huh, what are you thinking about when
you think of diastole? The resting phase, everything that we do, close your eyes, everything
that we do in medicine you should be able to conceptualize. If you're just reading what is
written here, if you just look at my mouth and listen what I have to say so be it, but you have
to be able to picture it. So, that's your resting phase. Isn't it? Hmmm, what's resting? How
about your blood vessels? Well, if your blood vessels get constricted, what happens, what's
that called please? Good. It's called TPR, total peripheral resistance and so therefore if there
is increased vasoconstriction of your blood vessel what phase of your blood pressure is
going to be affected, the systole or diastole please? The diastole. So, as we move forward or
any question that you get in terms of dissecting your blood pressure further, you want to
pay attention to why is the volume contributing to my systole or is it the fact that my blood
vessels and whether or not it's vasoconstricting or dilating affecting my diastole.