CUSM 5100 Week 2

Outstanding! Thanks to Dr. Peter, I can finally start to understand immunology. Highly recommend his lecture to annyone struggling with the subject.

The video by Lecturio provides an excellent overview of the electron transport chain and chemiosmosis, two of the most important metabolic processes in the cell. These processes work together to produce ATP, the cell's energy currency. One of the most interesting things about the electron transport chain is that it is a highly efficient way to convert energy from food into ATP. The chain uses the energy from NADH and FADH2, two electron carriers that are produced during glycolysis and the Krebs cycle, to pump protons across the inner mitochondrial membrane. This creates a proton gradient, which is like a dam holding back a reservoir of energy. The ATP synthase enzyme then uses the energy of the proton gradient to drive the synthesis of ATP from ADP and inorganic phosphate. This process is called chemiosmosis. The video does a great job of explaining the complex steps of the electron transport chain and chemiosmosis in a clear and concise way. It also provides helpful animations and diagrams that illustrate the process.

I've reviewed the Video, and while it provides a comprehensive overview, there are a few points that need clarification. "Fatty acid synthesis doesn't occur in the mitochondrion; it occurs in the cytoplasm, sequestered from fatty acid oxidation, simplifying the regulation of the two pathways." Clarification: Fatty acid synthesis indeed occurs in the cytoplasm, separate from fatty acid oxidation that takes place in mitochondria. This separation allows for streamlined regulation, ensuring the balance between synthesis and breakdown. "Fatty acid synthesis is chemically similar to the reverse of oxidation, involving joining, reduction, loss of water, and a final reduction, making it essentially the reverse of oxidation." Clarification: Fatty acid synthesis does indeed involve joining of acetyl and malonyl units, reduction steps, and removal of water, making it similar but not exactly the reverse of oxidation. The subtle differences in the chemical steps are crucial for the controlled synthesis of fatty acids. "The enzyme acetyl-CoA carboxylase is regulated through phosphorylation by AMP-activated protein kinase and allosteric binding of citrate, ensuring the balance between synthesis and cellular energy levels." Clarification: Acetyl-CoA carboxylase, a key enzyme in fatty acid synthesis, is indeed regulated through phosphorylation and allosteric binding of citrate. This regulation allows cells to respond to energy demands, modulating fatty acid production accordingly. "Fatty acid synthesis involves a series of steps catalyzed by the multifunctional enzyme fatty acid synthase, where individual activities within the enzyme complex work together, ensuring efficient fatty acid production." Clarification: Fatty acid synthase, a multi functional enzyme complex, plays a central role in fatty acid synthesis. Its individual activities work in harmony within the complex, allowing for the sequential addition of carbon units and the creation of fatty acids up to 16 carbons in length.

Great Lecturer..well explained. Every section of lectures are meticulously explained. Clearly understood.

I can easily follow the sequence of information. The important details are also emphasized, making it easier for recall.

Very clear and easy to understand. I enjoyed the visuals.

super clear, thank you very much. especially the graphics are pretty good, very explaining. lecturer explains well too.

Amazing Dr. Kevin! Thank you very much for this course!

Very annoying style of presentation. I do Cancer research for a living in the USA and I found a lot of problems with this presentation.

This lecture has solved all my problems about spinal cord.

Dr. Pickering has made this so easy to digest, understand and imagine. Have been struggling for days on this topic as well as lower limbs in general.

This lecture is amazing and I loved the explanation regarding the conformational change of hexocinase during the reaction.

I really liked the way that he explains, he makes very easy the learning of this topic, I'd recommend this class to all my partners

Outstanding review of connective tissue! These videos are helping me get so much more out of my studies!

Dr. Cornwall did a very great job with this.. The big picture simplified everything and made studying into little details easy.

I understood clearly this lesson about the posterior spaces of axyla

Whenever I get confused about a pathway, I come to watch these videos and it helps tremendously. Thank you for what you do.

the way he explains , dat is funny. I see some nerds didnt like the lecture, meh get a life "nerds" :D

He is a very Good Teacher as he teaches as if he was narrating a story.

Awesome analogy great lecture! Very nice lectures overall I really enjoyed them. even though I have taught this topics and I know them fairly well. I enjoy little gems of information I received through these lectures, and new understanding

Carlo Raj,'s way of presentation is little bit weird to me

Really good discussion. I would love Dr. Ahern to by my mentor

Very well explained lectures! I finally beginn to understand immunology instead of just learning it by heart. Thank you very much!

Professor Delves gave these lectures in such a logic and clear way. Very easy to follow and understand the talk. Great lectures!

HE has the lecturer super powers, funny sometimes too, makes you want to know more.

CT proper: mesenchyme, lax fibrillary, dense fibrillary, reticular, elastic, adipose and pigment. Supporting CT: cartilage and bone. Trophic CT: blood and lymph.

Good pictures Understanding the way he teaches Slow and steady

Well organised. Interesting. Coherent. As a result, it becomes very easy to absorb the information without getting confused.

The lecturer made the laminae look simple and memorable and definitely gotta be watched by peers since it gives a simple breaking down of presentation that makes it more easier to store it up.

Clear and Comprehensive explanation. Not too detailed but enough to understand.

He's pretty funny and has a clear lecture style. Very clearly laid out

Well taught and succinct. I enjoyed his style of lecturing, as he uses good intonations.

My last block contained a lot of immunology, and I did very poorly on the exam. I had an incredibly difficult time teasing out the most important information and organizing the immune response in a logical fashion. All the terms seemed jumbled in my head. This block is infectious disease, and requires building on the foundation of immunology--so I need to rebuild my foudation :p After watched just 3-4 of the Lecturio videos, I immensely regret not using it earlier. Thank you Dr. Delves, for being clear and logical it what is a very difficult and complex subject!

Very eloquent :) my favorite on this website! would definitely recommend.

Currently reviewing for my 3rd year of Medicine. Looking back even as much as osteology solidifies my knowledge in other aspects of muscle physiology and pathology. Dr. Pickering does a very good job of keeping you up to date and on pace

So well organized and clearly explained! The way you organize the material makes anatomy reasonable... the puzzle pieces fit.

Love him so far, clear concise and to the point and also very enlightening

Yea, these lessons site wide need more quiz questions. Only thing holding this site back from being outstanding.

Helped me a TON! Great quick easy overview of the Scapular bone, and was much easier to learn and understnad throughout this video. Much better understandment than my antomy class.

I am really enjoying this, helps me understand better and it makes it possible to review after I have had a lecture at my university or even before.

I would recommend this lecture to the osteopathic students snd colleagues

Very thorough explanation of the important structures found in the humerus. Recommended for medical students especially those who learn visually. Thank you, Dr. Pickering.

Very nice and clear explanations. Dr. Canby takes a very complicated topic and makes it easy to understand and remember. Thank you!

As much as your stories are interesting for the ETC gradient It does not fit my learning style. It would be nice to have clear scientific language about what's happening. I can't write a story on my exam paper. Perhaps this is just me.

concise and dramatic. Simple presentation well presented. A little spice in illustrations.

Easy to understand and very complete. Thank you for your time, helped me a lot

I love the clinical application. It makes it so much more exciting to learn and remember because as Dr Carlos Raj points out it's not just memorising. I must say his way of speaking makes it even more exciting :) On a serious note though-mentioning how serious it is to act on dysplasia or when the BM is involved-we should be saying omg, and not looking at him. Looking forward to more lectures-wish he was lecturing the subjects to keep that interest and significance of the subject and our job.

I rate this lecture with 5 stars because just after I heard this lecture I understood the 'Brachial Plexus'. That's why I recommend it to every medical student who want to understand the 'Brachial Plexus'. Thank you very much LECTURIO

Fantastic explanation about the topic, easy way to learn anatomy.

I don't like Carlo's style of presentation. It is also at odds with Robbins and Cotran. The worst video on Lecturio

very good lecture i thoroughly enjoyed watching and learning the content.

Dr. Pickering pointed out a few things that even my anatomy professor (who is excellent) did not. A very good lecture on the brachial plexus -- both short and detailed.

I will going to enter to the world of pathology next semester and i really didn't think i would like it but this videos might have changed my mind, Thanks Carlo for this material

This entire series is the most eloquent and beautiful explanation of a terrible terrible subject like biochemistry I have ever seen to attended

Really great explanations of the whole process. Was not happy that I had to relearn Krebs and ETC but actually found these videos enjoyable and valuable.

Very clear explanation and great presentation. Very easy to follow.

i like his voice, explains calmly and thoroughly. helped to understand anatomy in a nice easy way. thanks craig.

I cannot believe I am just now finding this resource during my dedicated Step 1 period. However, I am so glad that I found it now, right at the beginning of Step prep, rather than later. I plan to use this as one of my main resources for the remainder of time up until my exam. I realized while reading First Aid that, although I had known the subjects very well at one point, that my foundation was not as solid as it once was. This is perfect for reviewing and providing the big picture for everything. It's also an amazing resource for providing the "why" and "how" behind all the small factoids written in First Aid which is just what I need. It's so much easier to retain the information when you actually understand what is going on rather than memorizing a 650+ page book of bullet point lists/facts. This is great. I was a huge fan of Boards and Beyond, but I have since ditched that resource and am fully focusing on this one since this seems a lot more comprehensive and better taught (though Dr. Ryan has also done an amazing job too). Thank you guys so much for coming out with such a well thought out and developed and thorough resource. This is going to make board prep so much smoother. If I end up scoring highly on Step 1, I will make sure to write a review on Reddit, SDN, etc raving about Lecturio.

Gooood job LoL and really a good story-maker????Thank you very much! Amazing, very impressive!

I LIKE THE PRESENTATION AND I LEARN . PROFF. USE A SIMPLE AND UNDERSTANDABLE LANGUAGE

I finally understood why keto diet is so effective :) Thank you Dr. Kevin!

The Good: Lecture: 5/5 Amazing Lecture! I learned a lot! The Not so good: Quiz:2/5 Only 1 question....and was not as specific as I would like it to have been. Perhaps consider having at least 50% of the terms discussed included in the Quiz.

I find his lectures natural and easy to follow. He tells us areas we must take note of and what we absolutely need to remember. Complicated aspects are broken down and summarised simply. Will continue to listen to these lectures.

I certainly liked the video format, where we can adjust the focus from the speaker to the slide, and use the cursor to aid in pinpointing the relevant aspects of the scapula. The only thing I found was missing was a little aside about the suprascapular notch, which was shown in the slide, but not alluded to in the actual video lecture!

Best lecture ever, I never thought I'd be able to understand brachial plexus

I disagree with the comment below. I think he is a very good lecturer. Clear and concise. Yes, he does he have his unique gestures and tones, but so what? It's just different from the traditional, not wrong or anything. I found his lecture interesting. I don't think he was mocking anyone.

This course is very well organized. I am doing all my best to learn from it as much as I can.

a difficult topic made easy and clear - well done (this is just fillers to reach minimum word count needed to post review)

Couple of mistakes were made and he sounds as if he is mocking the audience

It was very simple and understandable. I could keep up without being confused.

Carlo makes the content interesting and manageable with intonation and examples.

I love everything about it. Not only knowledgeable but a gifted speaker

it was very good lecture it will help me in my med biochem class thanku

really nice ,lecture and also good questions at the end to assess,thank you