Overview – Reproductive Pharmacology

00:01 Welcome to Pharmacology by Lecturio.

00:03 I'm Dr. Pravine Shukle.

00:05 We're going to be covering some reproductive pharmacology today.

00:09 Listen, this is a huge topic.

00:12 You can see all the different subtypes and categories on the screen beside me.

00:17 The gonadal hormone antagonists and agonists sometimes do the same thing and sometimes they do the opposite thing of what you expect.

00:24 We're going to spend a lot of time in each section and we're going to go over them in detail, so that you understand them and you feel confident answering questions on exams.

00:33 We're going to be talking about estrogens and anti-estrogens.

00:37 We’ll be talking about progestins and anti-progestins and we're going to be talking about androgens and anti-androgens.

00:44 With respect to the anti-estrogen medications, there's a whole bunch of subtypes there.

00:49 There are the receptor antagonists.

00:52 There are aromatase inhibitors and then there are GnRH agonists, like danazol, and antagonists, which interestingly enough do the same thing.

01:02 Underneath the receptor antagonist section – this is estrogen receptor antagonists – we have full antagonists and we have selective antagonists.

01:13 With respect to the progestins, we have actual progestin that we administer and we have an anti-progestin called mifepristone.

01:21 With respect to the androgens, we have a whole list of medications.

01:25 We have anti-androgens that are receptor antagonists.

01:29 We have 5-α-reductase inhibitors.

01:32 We have synthesis inhibitors.

01:34 And we have other ones such as the GnRH agonists and antagonists.

01:40 When we take a look at reproductive pharmacology, just have a look at this diagram.

01:44 I won't go over it in detail now because each section of this diagram will be placed beside the specific area that we’re talking about.

01:52 This just gives us an overview.

01:54 So, have a look at it on your own time.

01:55 It's a very good diagram to understand how all of the drugs fit in.