00:01
Hi. Welcome to our video on cholesterol-
lowering medications.
00:06
Now, we call those the statins,
and I'll explain why.
00:09
They have a pretty long name, but
we'll get to that in just a minute.
00:12
So cholesterol gets a pretty bad reputation,
but it's part of every one of
our cell membranes.
00:18
We need cholesterol. We need
it to make hormones, like
estrogen and progesterone or testosterone.
00:26
So, cholesterol does some pretty cool things
in your body. Let's look at a few others.
00:30
We also need it to make bile salts. Now
that doesn't sound really glamorous,
but you need bile salts to break down fats.
00:38
So, so far, we know that cholesterol
helps us make hormones,
we need it to make bile salts, and
it's also used in the skin.
00:46
Kind of helps with evaporation of
water and absorption of some
water-soluble compounds. So
it helps our hormones,
it helps us make bile salts to break
down fats, and it makes our skin
beautiful, and also helps
us with absorption.
01:01
So cholesterol is really a necessary and
important part of all of our cells.
01:06
Now, where do we get cholesterol?
Well, there's 2 main sources.
01:10
We get it in our diet, and we call that
exogenous, that's coming from
outside of our body.
01:15
Now, if you take an increase
of saturated fats,
that causes the most significant increase
in your serum blood cholesterol.
01:22
Now we've got a picture there
for you. It's a fish.
01:25
That is not saturated fat.
01:27
That's what you should try moving your
diet towards are more fish, rather than
beef and butter and cream and milk.
01:36
Those are all dietary sources
of saturated fats,
but fish is going to be a healthier
source for you. Yeah,
I'll keep trying to sell you on that later.
01:45
Now, the second source of cholesterol
is made by cells in our own body.
01:49
It's primarily in the liver, and you'll see
we have the term there, "endogenous,"
that's from inside. So where do
we get cholesterol?
2 places, from our diet
and from the cells in our body,
primarily in the liver.
02:02
Okay. So why is HDL considered
the "good" cholesterol
and LDL considered the "bad" cholesterol?
So stop for just a minute and see if
you really can think through
why one cholesterol is considered good
and one is considered bad.
02:21
Okay, let's break down the numbers.
02:23
HDL versus LDL.
02:25
So let's look at LDL first.
02:27
It's about 60%-70% of your total
serum cholesterol.
02:31
Now, the role and the job of this LDL
is it delivers cholesterol to the tissues.
02:37
Now when you have an elevated level of
LDL, meaning it's higher than is healthy,
you have an increased risk for
atherosclerosis. Okay, that means
hardening of the arteries and
you have this buildup,
and it really puts you at significant
risk for cardiovascular events.
02:52
So that's why LDL gets its nickname
of the "bad" cholesterol.
02:58
You've got to have some of it, but
if you have too much of it,
you're really increasing your
risk for an adverse,
really bad cardiovascular event, like
a heart attack or stroke.
03:09
Now HDL, the "good" cholesterol, is about 20%-30%.
03:14
Now it carries cholesterol from
the tissues back to the liver.
03:18
That's why we consider it the good one.
03:20
If you have elevated levels of HDL,
then you're going to decrease
your risk of atherosclerosis.
03:26
So our goal for our patients, and
should be for ourselves,
is we want to elevate our
HDL levels and try to
keep our LDL levels at a minimum.
03:35
You need them both, but you
need a really healthy balance.