Two Hit Hypothesis
About the Lecture
The lecture Two Hit Hypothesis by Georgina Cornwall, PhD is from the course Cell Cycle and Cell Division.
Included Quiz Questions
What would be a good analogy for a cell with a mutation in both copies of a tumor suppressor gene?
- A car with a brake pedal that does not work
- A car whose gas pedal gets stuck when pushed down
- A car whose gas pedal does not work
- A car that has a gas pedal stuck in an accelerated position
- A car that does not have air conditioning
p53 is a tumor suppressor. What must happen for a tumor suppressor gene to have cancer-causing abilities?
- The gene on both chromosomes must acquire a mutation.
- The gene must undergo one mutation.
- The gene must get replicated several hundred times for it to become cancerous.
- The gene should attach to the promoter region of the oncogenes nearby.
- The gene on one chromosome must undergo three mutations.
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Author of lecture Two Hit Hypothesis
Georgina Cornwall, PhD
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