Transcriptional Control
About the Lecture
The lecture Transcriptional Control by Georgina Cornwall, PhD is from the course Gene Regulation.
Included Quiz Questions
Which of the following are necessary components of the initiation complex in eukaryotes? Select all that apply.
- Multiple transcription factors
- RNA polymerase II
- Transcription-associated factors (TAFs)
- Activator proteins
- Enhancer regions
Why are transcription factors able to bind far away from the gene they are aiming to transcribe?
- DNA looping orients the transcription factor closer to the promoter to initiate gene transcription.
- The transcription factor transcribes small RNAs that then bind to the promoter and activate gene expression.
- Signals originate via inducers from the transcription factor to the site of promotion, activating gene transcription.
- RNA looping moves the transcription factor closer to the promoter.
- Transcription factors denature and loop back to the promoter to initiate transcription.
Which of the following is true of an enhancer?
- It can be located away from the gene, upstream or downstream from the starting point of transcription.
- It is a cis-acting region of nucleic acids composed of 50–1500 base pairs.
- It is a part of the core promoter region composed of -35 and -10 elements.
- It is a part of the promoter region, where RNA pol starts to unwind the DNA duplex.
- It is a part of a polycistronic gene where a repressor attaches.
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Author of lecture Transcriptional Control
Georgina Cornwall, PhD
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