Introduction to the Citric Acid Cycle by Kevin Ahern, PhD

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About the Lecture

The lecture Introduction to the Citric Acid Cycle by Kevin Ahern, PhD is from the course Carbohydrate Metabolism. It contains the following chapters:

  • Introduction to the Citric Acid Cicle
  • Ketone Body Metabolism

Included Quiz Questions

  1. Acetyl CoA
  2. Ethanol
  3. Glucose
  4. Lipoamide
  5. Acetaldehyde
  1. Tyrosine
  2. Glutamine
  3. Glutamate
  4. Proline
  5. Arginine
  1. The citric acid cycle enables the yeast or a bacterial cell to get metabolic energy from acetyl Co-A in the absence of oxygen.
  2. The catabolic breakdown of amino acids produces the intermediates of the TCA cycle.
  3. During anabolism of amino acids, the intermediates of the TCA cycle are used to synthesize the amino acids like glutamine, glutamate, proline, and arginine.
  4. The oxaloacetate, a TCA cycle intermediate, acts as a precursor for the synthesis of aspartate, asparagine, methionine, and threonine.
  5. In the absence of oxygen, the acetyl Co-A can’t enter the TCA cycle, so the yeast produces energy by converting pyruvate to ethanol.
  1. The pyruvate dehydrogenase enzyme converts the acetaldehyde to ethanol in the yeast cell in the absence of oxygen.
  2. The pyruvate dehydrogenase enzyme is a mitochondrial enzyme.
  3. The pyruvate dehydrogenase enzyme is a very large multimeric complex composed of three subunits named E1, E2, and E3
  4. The E2 subunit of pyruvate dehydrogenase enzyme converts the TPP-acetaldehyde to acetyl-lipoamide, whereas the E3 subunit coverts the acetyl-lipoamide to acetyl-CoA.
  5. The enzyme pyruvate dehydrogenase converts the pyruvate to acetyl Co-A via decarboxylation in the presence of oxygen.

Author of lecture Introduction to the Citric Acid Cycle

 Kevin Ahern, PhD

Kevin Ahern, PhD


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