Gene Expression Control – Metabolic Control of Enzyme Activity by Kevin Ahern, PhD

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About the Lecture

The lecture Gene Expression Control – Metabolic Control of Enzyme Activity by Kevin Ahern, PhD is from the course Metabolic Control.


Included Quiz Questions

  1. Nucleotide
  2. Transcriptional
  3. RNA stability
  4. Translational
  1. HIF-1
  2. HIF-2
  3. GLUT1
  4. GLUT2
  5. Two transcription factors, called GLUT1 and GLUT3.
  1. The HIF-1 factor helps the cell to combat toxic conditions that originated due to higher oxygen levels.
  2. Under hypoxia conditions, the regular cells, as well as cancer cells, synthesize the transcription factor called HIF-1.
  3. HIF-1 factor favors elevated levels of expression of the seven enzymes of the glycolysis pathway during hypoxia condition.
  4. HIF-1 factor binds to the particular class of genes in the DNA which helps in the survival of cells at low oxygen concentrations.
  5. The transcription factor HIF-1 helps in the movement of glucose to the interior of the cell by favoring the formation of GLUT1 and GLUT3 proteins.
  1. Controlling the process of transcription and hence synthesis of specific mRNA and protein molecules.
  2. Controlling the permeabilities of the cell membrane and mitochondrial membrane for water.
  3. Controlling the fluidity of cell membrane by regulating ion movement.
  4. Controlling the amounts of energy in the form of ATP and GTP.
  5. Controlling the amounts of rRNA and tRNA to regulate.

Author of lecture Gene Expression Control – Metabolic Control of Enzyme Activity

 Kevin Ahern, PhD

Kevin Ahern, PhD


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